Stress is an integral part of everyday modern life and refers to a state in which the internal balance of the organism is disturbed. Lazarus and Folkman defined stress as a special relationship between a person and the environment, which a person evaluates as very demanding or as a relationship that exceeds his capabilities and threatens his well-being. Different stimuli can cause stress in individuals. The presence of a stimulus does not cause stress, but stress is caused by the subjective meaning that an individual attaches to that stimulus. An increasing number of research studies the effect of psychosocial stress on the development and course of various diseases, such as: ischemic heart disease, cardiac arrhythmias, elevated arterial blood pressure, ulcer disease, hyperthyroidism, diabetes, asthma, rheumatic diseases... Stress has a great impact on endocrine , neurotransmitter and immune system, which often manifests itself as skin diseases. The skin is the largest organ of the human body, it is called the "organ of communication/expression", it is responsible for numerous functions and plays an important role in protecting the body and internal organs. Psychodermatology is a science that covers all aspects of the relationship between the psychological status and the skin regarding the cause, onset, development, diagnosis and treatment of various skin diseases. The role of stress and stressful events in psoriasis, alopecia areata, atopic dermatitis, acne and vitiligo was especially investigated. The aim of this paper is to present the results of research and expert knowledge that explain the connection between psychological stress and skin diseases, and to present treatment methods. Treatment of skin diseases is difficult if stress is not recognized as an exacerbating factor. Numerous physiotherapy procedures have been shown to be effective in reducing stress. Physiotherapy techniques that help reduce psychological stress and treat skin diseases are: physical activity, massage, breathing exercises, progressive muscle relaxation, iontophoresis and phototherapy.